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独活素以浓度依赖的方式抑制人原代T细胞中T细胞受体介导的增殖。赫拉克林还诱导细胞凋亡。当imperatorin在细胞周期的G1 / S期诱导DNA片段化时，独活素在细胞周期的G2 / M期诱导DNA片段化，因此尽管结构相似，它们仍以机械方式不同的方式诱导凋亡。 Heraclenin inhibits T cell-receptor-mediated proliferation in human primary T cells in a concentration-dependent manner. Heraclenin also induces apoptosis. While imperatorin induces DNA fragmentation at the G1/S phase of the cell cycle, heraclenin induces DNA fragmentation at the G2/M phases of the cell cycle, thus despite a close structural similarity they induce apoptosis in mechanistically different ways.

Specs ⸢ View details ⸥

Chinese name

独活素

English name

Heraclenin

Chinese alias

独活内酯 | (R)-9-((3,3-二甲基环氧乙烷-2-基)甲氧基)-7H-呋喃并[3,2-g]苯并吡喃-7-酮

English alias

CAS number

2880-49-1

molecular formula

C16H14O5

molecular weight

286.28 g/mol

Exact mass

≥98%

PSA

61.200 Å²

Logp

2.200

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Research chemical CAS 2880-49-1 HPLC ≥98% 5mg

Name: Research chemical CAS 2880-49-1 HPLC ≥98% 5mg
Brand: 源叶
SKU: B20316-5mg

Yuanye Research chemical CAS 2880-49-1 HPLC ≥98% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：B20316-5mg

Product model：5mg

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Research chemical CAS 2880-49-1 HPLC ≥98% 5mg

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