Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans , improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway In Vitro Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: 3T3-L1 cell. Concentration: 1-500 μM. Incubation Time: 48 h. Result: Did not cause significant cell death up to 500 μM concentration. Cell Viability AssayCell Line: 3T3-L1 cell. Concentration: 5 μM, 10 μM, 15 μM. Incubation Time: 8 days (replaced every 2 days). Result: LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation. Form:Solid IC50& Target:PPARγ GLUT4