
- exposure pathway: 静脉注射。口服后吸收不良。
- Toxicity summary: 米托蒽醌是一种通过氢键与脱氧核糖核酸(DNA)相互作用的DNA反应性试剂,可引起交联和链断裂。米托蒽醌还干扰核糖核酸(RNA),并是拓扑异构酶II的有效抑制剂,该酶负责解开和修复受损DNA。它对增殖和非增殖培养的人体细胞都具有细胞毒性,表明缺乏细胞周期特异性。
- Regulatory information: 加州化妆品安全计划(CSCP)报告成分:报告 - 无论成分在产品中的预期功能如何
- Health Effects: 心肌病是一个特别值得关注的影响,因为它不可逆。[维基百科]
- Hepatotoxicity: 可能性评分: D(可能是临床上明显的肝损伤的罕见原因)。
- Symptoms and Signs: 严重白细胞减少伴感染。
- Hazard categories and classifications: 水环境慢性2(100%)
- Carcinogen Classification: 2B,可能对人类致癌。(L135)
- Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
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Research chemical CAS 65271-80-9 HPLC ≥97% 1g
Yuanye Research chemical CAS 65271-80-9 HPLC ≥97% 1g, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.




