中文介绍： BMS-1001 是一种有效的 PD-1/PD-L1 相互作用的抑制剂，EC50值为253 nM。BMS-1001 可减轻可溶性PD-L1对T细胞受体介导的T淋巴细胞活化的抑制作用。 Information BMS-1001 BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. Targets PD-1/PD-L1 (Cell-free assay) 253 nM(EC50) In vitro BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is effective in attenuating the inhibitory effect of the cell surface-associated PD-L1. Cell Research(from reference) Cell lines：PD-L1 + aAPC/CHO-K1 cells (aAPCs), PD-1 Effector Cells (ECs) Concentrations：0.12 μM, 0.3 μM, 1.2 μM, 3 μM Incubation Time：24 h