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Product introduction

Basmisanil (RG1662) 是一种高选择性含 α 亚基 GABAA 受体 (GABAAα5) 的负变构调节剂，具有口服活性。Basmisanil 可以抑制 GABAA-α5， Ki 值为 5 nM 和 IC50 值为 8 nM。Basmisanil 可用于多种认知和精神障碍的研究。

Specs ⸢ View details ⸥

Chinese name

巴米沙尼, GABA A 受体 α5 亚基的异构调节剂

English name

Basmisanil

Chinese alias

example 112 [WO2009071476] | RG-1662 | RG1662

English alias

DB11877 | EX-A1272 | (1,1-dioxo-1,4-thiazinan-4-yl)-[6-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]pyridin-3-yl]methanone | (1,1-Dioxo-4-thiomorpholinyl)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone | AC-35398 | Ba

CAS number

1159600-41-5

molecular formula

C21H20FN3O5S

molecular weight

445.46 g/mol

Exact mass

PSA

111.000 Å²

Logp

1.9

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