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BI 3231 是一种有效和选择性的羟基类固醇 17ß-脱氢酶 13 HSD17B13 抑制剂，对 hHSD17B13 和 mHSD17B13 的 IC50 值分别为 1 和 13 nM。BI 3231 具有研究非酒精性脂肪性肝炎 (NASH) 和其他肝脏疾病的潜力。 BI 3231 is a potent and selective hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases.

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Chinese name

BI-3231, 羟基类固醇 17-beta 脱氢酶 13 抑制剂

English name

BI-3231

Chinese alias

BI3231;compound 45

English alias

BI3231;compound 45

CAS number

2894848-07-6

molecular formula

C16H14F2N4O3S

molecular weight

380.37 g/mol

Exact mass

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