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Product introduction

BPKDi 是一种有效的联吡啶 PKD 抑制剂，对 PKD1、PKD2 和 PKD3 的 IC50 分别为 1 nM、9 nM 和 1 nM。BPKDi 阻断心肌细胞中 IIa 类 HDAC 的信号依赖性磷酸化和核输出 BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes

Specs ⸢ View details ⸥

Chinese name

BPKDi, 蛋白激酶 D1 抑制剂

English name

BPKDi

Chinese alias

English alias

2-[2-(cyclohexylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide | 2′-(cyclohexylamino)-6-(1-piperazinyl)-[2,4′-bipyridine]-4-carboxamide

CAS number

1201673-28-0

molecular formula

C21H28N6O

molecular weight

380.49 g/mol

Exact mass

PSA

96.200 Å²

Logp

2.2

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