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溶于水、乙醇、丙酮、苯、甲苯、二甲苯、二氯乙烷、氯仿、乙酸、乙酐、乙酸乙酯、已烷、四氢呋喃、三乙胺、吡啶、DMF 等溶剂,水中溶解度:76 g/l (25°C)。酰化反应的高效催化剂 4-二甲氨基吡啶(DMAP)是一种多功能亲核催化剂,用于酰化和酯化反应。它也可用于各种有机转化反应,如Baylis-Hillman反应、Dakin-West反应、胺的保护、C-酰化、硅烷化、天然产物化学中的应用。 应用 4-二甲氨基吡啶可用作以下反应的催化剂: 通过与丙二腈、醛和β-硝基烯反应合成3,5 取代的2,6-二氰基苯胺。 在无辅助碱和溶剂的条件下与酸酐进行醇的酰化反应合成相应的酯。 通过活化烯和醛或酮的偶联进行Baylis-Hillman 反应生成碳碳键。 酰化反应的高效催化剂。 A highly efficient catalyst for acylation reactions 4-Dimethylaminopyridine (DMAP) is a versatile nucleophilic catalyst used in acylation and esterification reactions. It can also be used in various organic transformations such as Baylis-Hillman reaction, Dakin-West reaction, protection of amines, C-acylation, silylation, and applications in natural product chemistry. Application 4-Dimethylaminopyridine can be used as a catalyst for the following reactions: Synthesis of 3,5-substituted 2,6-dicyanoanilines by reaction with malononitrile, aldehydes and β-nitroolefins. Acylation of alcohols with anhydrides to synthesize the corresponding esters in the absence of auxiliary bases and solvents. Baylis-Hillman reaction to generate carbon-carbon bonds by coupling of activated alkenes with aldehydes or ketones. Efficient catalyst for acylation reactions.
Chinese name
4-二甲氨基吡啶
English name
4-Dimethylaminopyridine
Chinese alias
N-(4-吡啶基)二甲基胺 | N,N-二甲基-4-吡啶胺 | 4-(二甲氨基)吡啶
English alias
N,N-dimethyl 4-pyridinamine | p-dimethylamino pyridine | (4-DMAP);4-Dimethylaminopyridine | 4-di methylaminopyridine | 4-Dimethylaminepyridine | N,N-dimethyl-N-(4-pyridinyl)amine | dimethyl-pyridin-4-yl-amine | dimethyl-pyridin-4yl-amine | dimethylpyridin
CAS number
1122-58-3
molecular formula
C7H10N2
molecular weight
122.17 g/mol
Exact mass
≥99%
PSA
16.100 Ų
Logp
1.300
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Research chemical CAS 1122-58-3 HPLC; ≥99%; 100mg

Research chemical CAS 1122-58-3 HPLC; ≥99%; 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: HPLC; ≥99%; 100mg.

item number:B65287-100mg
Product model:100mg
level: HPLC; ≥99%; 100mg
Lead Time:30days
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