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Product introduction

BMS-986176 (LX-9211) 是一种有效的，高选择性、可穿过血脑屏障的 AAK1 (adaptor associated kinase 1) 抑制剂，IC50 为 2 nM。BMS-986176 可用于神经退行性疾病的研究。 BMS-986176 (LX-9211) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM. BMS-986176 can be used for neurodegenerative diseases research.

Specs ⸢ View details ⸥

Chinese name

BMS-986176, AP2 相关激酶 1 抑制剂

English name

BMS-986176

Chinese alias

BMS986176 | LX-9211 | LX9211

English alias

US10155760, Example 123 | BMS-986176 | 1815613-42-3 | 9G4RLM5X6Z | UNII-9G4RLM5X6Z | LX9211 | LX-9211 | AAK1-IN-1 | (2S)-1-((2',6-Bis(difluoromethyl)(2,4'-bipyridin)-5-yl)oxy)-2,4-dimethyl-2-pentanamine

CAS number

1815613-42-3

molecular formula

C19H23F4N3O

molecular weight

385.40 g/mol

Exact mass

PSA

61.000 Å²

Logp

3.7

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