- exposure pathway： 口服给药后迅速吸收。
- Toxicity summary： 佐匹克隆通过与苯二氮䓬受体复合物结合并调节GABA<sub>B</sub>Z受体氯离子通道大分子复合物发挥作用。佐匹克隆和苯二氮䓬类药物作为完全激动剂，在含有alpha1、alpha2、alpha3和alpha5 GABAA受体的苯二氮䓬结合位点上无区别地起作用，增强GABA的抑制作用，产生佐匹克隆的治疗(催眠和抗焦虑)和不良反应。
- Regulatory information： 新西兰化学品状态清单：佐匹克隆：没有单独批准，但可作为符合团体标准的产品成分使用。它不被批准作为化学品单独使用。
- Health Effects： 它们会导致言语不清、定向障碍和"醉酒"行为。它们具有生理和心理成瘾性。
- Symptoms and Signs： 在欧洲上市后报告中，有少数关于过量服用消旋佐匹克隆导致致命结果的个别病例报告，这些病例大多与其他中枢神经系统抑制剂过量相关。中枢神经系统抑制剂过量作用的体征和症状可预期表现为临床前测试中观察到的药理作用的加剧。
- Hazard categories and classifications： 生殖毒性 2 (92.8%)
- Carcinogen Classification： 对人类无致癌性迹象（未被IARC列出）。
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
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Research chemical CAS 43200-80-2 99% 100mg
Yuanye Research chemical CAS 43200-80-2 99% 100mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
