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Product introduction
BGJ398 (NVP-BGJ398)是一种有效的,选择性的FGFR抑制剂,作用于FGFR1/2/3,IC50为0.9 nM/1.4 nM/1 nM,作用于FGFR比作用于FGFR4和VEGFR2选择性高40倍以上,对Abl, Fyn, Kit, Lck, Lyn和Yes几乎没有抑制活性。Phase 2。 BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2. A potent and selective inhibitor of Flg (FGFR-1), Bek (FGFR-2), FGFR-3 and FGFR-4.
Chinese name
BGJ398 (NVP-BGJ398), 成纤维细胞生长因子受体抑制剂
English name
BGJ398 (NVP-BGJ398)
Chinese alias
-
English alias
BGJ398 (NVP-BGJ398) | 872511-34-7 (free base) | AKOS000295891 | WHO 10032 | 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea | BCP0726000187 | DB11886 | Infigratinib | Q27075200 | SCHEMBL374435
CAS number
872511-34-7
molecular formula
C26H31Cl2N7O3
molecular weight
560.48 g/mol
Exact mass
-
PSA
95.100 Ų
Logp
4.7
Technical Documents
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BGJ398 (NVP-BGJ398) ≥98% 5mg

BGJ398 (NVP-BGJ398) ≥98% 5mg CAS 872511-34-7, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:B864633-5mg
Product model:5mg
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Lead Time:30days
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