
- DOT label: 化学类别 -> 挥发性有机化合物
- Health hazard: 它被归类为剧毒。人类可能的口服致死剂量小于5毫克/千克,或对于一个70公斤(150磅)的人来说,少于7滴的味道。通过皮肤吸收具有很高毒性。(EPA, 1998)
- reactive group: 酸酐
- Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
- First aid measures: 6. 立即送往医疗机构! (EPA, 1998)
- Regulatory information: 新西兰EPA化学品清单状态:斑蝥素:HSNO批准:HSR006361 批准但有控制措施
- fire hazard: 加热分解时会产生刺激性烟雾和刺激性气体。(EPA, 1998)
- fire fighting: FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)
- interaction: 斑蝥素在含有琥珀酸钠或D,L-β-羟基丁酸钠的培养基中,会导致大鼠肝脏线粒体的氧化磷酸化解偶联。
- reactivity profile: 有机酸酐,如斑蝥素,与酸、强氧化剂、醇、胺和碱不相容。
- Isolation and evacuation: 火灾:如果涉及罐、铁路罐车或公路罐车,应在所有方向上隔离800米(1/2英里);同时,考虑在所有方向上初始疏散800米(1/2英里)。(ERG, 2024)
- Air and water reaction: 与空气无快速反应。与水无快速反应。
- non-human toxicity value: LD50 小鼠腹腔注射 1 毫克/千克
- Hazard categories and classifications: L-丝氨酸在细胞生长和发育(细胞增殖)中发挥作用。L-丝氨酸通过丝氨酸羟甲基转移酶转化为甘氨酸,形成嘌呤碱基腺嘌呤和鸟嘌呤合成所需的一碳单位。这些碱基与戊糖磷酸酯连接时,是DNA和RNA的必需成分,也是能量产生代谢途径的最终产物ATP和GTP。此外,L-丝氨酸通过相同的酶转化为甘氨酸,为产生嘧啶核苷酸脱氧胸苷一磷酸提供了一碳单位,这也是DNA的必需成分。
- Non-fire leakage response: 避免吸入和皮肤接触。(美国环保署, 1998)
- Personal protective equipment (PPE): 紧急情况下,佩戴正压、需求式、全面罩自给式呼吸器(SCBA)或需求式供气呼吸器,并配备逃生SCBA和全包覆式耐化学腐蚀服。(EPA, 1998)
- Antidote and first aid: 高级治疗:对于意识不清、严重肺水肿或呼吸停止的患者,考虑经口或经鼻气管插管以控制气道。在上呼吸道阻塞的最初迹象出现时,可能需要早期插管。使用气囊面罩装置进行正压通气技术可能有益。监测心律,必要时治疗心律失常... ... 建立静脉输液,使用D5W/SRP:"保持开放",最小流速/。如果出现低血容量迹象,使用乳酸盐林格氏液。注意液体过载的迹象。考虑使用药物治疗肺水肿... ... 使用地西泮(Valium)治疗癫痫... ... 使用盐酸丙美卡因辅助眼睛冲洗... . /刺激性材料/
- Protective Action Standards (PAC): PAC-3: 27 [mg/m3]
- Carcinogen Classification: IARC专著:第7卷补充:致癌性总体评价:IARC专著第1至42卷的更新,1987年;440页;ISBN 92-832-1411-0 (已绝版)
- Natural Pollution Sources: 斑蝥素是粗药斑蝥中的活性成分,从干燥的斑蝥虫(Cantharis vesicatoria)中获得。
- Evidence for Carcinogenicity: 致癌性分类:1)人类证据:不充分数据;2)动物证据:有限证据。对人类致癌风险的总体总结评价为3组:该物质对人类的致癌性无法分类。/摘自表格/
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Research chemical 0. 1 mg
Research chemical 0. 1 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 0. 1 mg.




