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Product introduction

CBL0137 (Curaxin-137)是一种 histone chaperone FACT (facilitates chromatin transcription) 的抑制剂，可同时抑制 NF-κB 并激活 p53，对应的EC50值分别为0.47 μM和0.37 μM。 Information CBL0137 CBL0137 (Curaxin-137) is an inhibitor of the histone chaperone FACT (facilitates chromatin transcription) that simultaneously suppresses NF-κB and activates p53 with EC50 of 0.47 μM and 0.37 μM, respectively. Targets FACT ; p53 (Cell-free assay); NF-κB (Cell-free assay) ; 0.37 μM(EC50); 0.47 μM(EC50)

Specs ⸢ View details ⸥

Chinese name

CBL0137

English name

CBL0137

Chinese alias

English alias

Pentaerythritol, sodium salt | 1,1'-{9-[2-(propan-2-ylamino)ethyl]-9H-carbazole-3,6-diyl}diethanone | 1-[6-acetyl-9-[2-(isopropylamino)ethyl]carbazol-3-yl]ethanone | cbl0137 | CBL-0137 | CBL-0137; CBL 0137; Curaxin 137 | 1197996-80-7 | Curaxin 137 | CBLC1

CAS number

1197996-80-7

molecular formula

C21H24N2O2

molecular weight

336.43 g/mol

Exact mass

≥98%

PSA

51.100 Å²

Logp

3.338

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