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Product introduction

Information C25-140 C25-140 is a small-molecule inhibitor of TRAF6-Ubc13 interaction . C25-140 directly binds to TRAF6, thereby blocking the interaction of TRAF6 with Ubc13, and as a consequence lowers TRAF6 activity. C25-140 impedes NF-κB activation in various immune and inflammatory signaling pathways also in primary human and murine cells. Targets TRAF6-Ubc13 ; NF-κB

Specs ⸢ View details ⸥

Chinese name

C25-140

English name

C25-140

Chinese alias

1-(4-Benzylpiperidin-1-yl)-3-(3,5-dimethyl-1-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl)propan-1-one

English alias

1-Propanone,3-[3,5-dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-

CAS number

1358099-18-9

molecular formula

C26H31N7O

molecular weight

457.57 g/mol

Exact mass

≥98%

PSA

81.200 Å²

Logp

3.600

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