
- Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
- interaction: 描述了一种方法,用于确定氯环嗪盐酸盐(I)抗组胺活性是否可以在与0.5%氢化可的松醋酸酯(Mantadil; II)乳膏联合外用时得到证实。在30名受试者中研究了氢化可的松5%、II和安慰剂乳膏。数据显示,在受试者中诱导的风团和潮红反应被组合物中的I成分减少。/氯环嗪盐酸盐/
- Human toxicity extract: 在H1拮抗剂急性中毒中,其中枢兴奋效应构成最大危险。该综合征包括幻觉、兴奋、共济失调、不协调、手足徐动症和惊厥。固定、扩大的瞳孔伴有潮红的脸,加上窦性心动过速、尿潴留、口干和发热,使该综合征与阿托品中毒综合征有显著相似性。最终,深度昏迷伴有心肺衰竭和死亡,通常在2至18小时内发生。/H1拮抗剂/
- Hazard categories and classifications: 水生急性1级(100%)
- Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
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