必需脂肪酸缺乏症的症状包括免疫系统下降和炎症抑制的一般状态。CP 24,879是花生四烯酸生物合成的抑制剂，通过抑制Δ5/Δ6去饱和酶起作用。以3 mg / kg的CP 24,879注射的小鼠肝花生四烯酸含量降低约50％。用5 µM CP 24,879处理的鼠肥大细胞瘤细胞显示出增加的米德酸含量和白三烯C4合成的几乎完全消融，这与去饱和酶抑制诱导的必需脂肪酸缺乏状态一致。 Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition. CP 24,879 is an inhibitor of arachidonic acid biosynthesis acting via the inhibition of Δ5/Δ6 desaturase. Mice injected with CP 24,879 at 3 mg/kg had a reduction of liver arachidonate content of approximately 50%. Murine mastocytoma cells treated with 5 μM CP 24,879 showed increased mead acid content and nearly complete ablation of leukotriene C4 synthesis, consistent with a desaturase inhibition-induced state of essential fatty acid deficiency.