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Product introduction

琥珀酰亚胺酯（NHS，胺反应活性）官能化环辛烷衍生物，用来将环辛烷部分插入含有化合物或生物分子的氨基找那个。环辛烷可以用于种促进免铜电极化学环加成反应。这一聚乙二醇会和叠氮官能化化合物或生物分子反应，而不需要Cu（I）催化，就能形成稳定的三唑连接。应用包括：蛋白质-多肽偶联物；抗体-酶或抗体药物偶联物；蛋白质或多肽-寡核苷酸偶联物；表面修饰。聚乙二醇-PEG4-N-氢化琥珀酰亚胺酯可以通过少铜点击反应，用来合成前列腺特异性膜抗体（PSMA）目标单光子发射计算体层摄影（SPECT）试剂。 Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Product Describtion: DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

Specs ⸢ View details ⸥

Chinese name

DBCO-PEG4-NHS酯

English name

DBCO-PEG4-NHS Ester

Chinese alias

DBCO-PEG4-琥珀酰亚胺脂 | 20-(11,12-二脱氢二苯并[b,f]吖辛因-5(6H)-基)-17,20-二氧代-4,7,10,13-四氧杂-16-氮杂二十酸2,5-二氧代-1-吡咯烷基酯 | 二苯并环辛炔-PEG4-琥珀酰亚胺酯

English alias

Dibenzocyclooctyne-PEG4-Nhydroxysuccinimidyl ester | DBCO-PEG4-NHS ester | DBCO-PEG4-SE | DBCO-PEG4-succinimidyl ester | DBCO-NH-PEG4-CH2CH2COONHS ester

CAS number

1427004-19-0

molecular formula

C34H39N3O10

molecular weight

649.70 g/mol

Exact mass

≥95%

PSA

150.000 Å²

Logp

0.400

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