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Product introduction

DIM-C-pPhOH 是核受体 4A1 (NR4A1) 拮抗剂。DIM-C-pPhOH 抑制癌细胞的生长和 mTOR 信号传导，诱导细胞凋亡和细胞应激。DIM-C-pPhOH 可降低细胞增殖，对 ACHN 细胞和 786-O 细胞的 IC50 值分别为 13.6 μM 和 13.0 μM。 product description： DIM-C-pPhOH is a nuclear receptor 4A1 (NR4A1) antagonist. DIM-C-pPhOH inhibits cancer cell growth and mTOR signaling, induce apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively。

Specs ⸢ View details ⸥

Chinese name

DIM-C-pPhOH,Nur77拮抗剂

English name

DIM-C-pPhOH

Chinese alias

1,1-双(3'-吲哚基)-1-(对羟基苯基)甲烷 | 4-[二(1H-吲哚-3-基)甲基]苯酚 | (4-羟基苯基)双(1H-吲哚-3-基)甲烷

English alias

CAS number

151358-47-3

molecular formula

C23H18N2O

molecular weight

338.408 g/mol

Exact mass

PSA

51.800 Å²

Logp

5.200

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