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Product introduction

DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC 50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC 50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity In Vitro DDR1-IN-5 (compound 121; for 24 hours) inhibits collagen production in human hepatic stellate cell LX-2 (IC 50 =62 nM). DDR1-IN-5 (72 hours) has cytotoxicity in LX-2 cells (CC 50 >40 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:DDR1 7.36 nM (IC 50 )

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Chinese name

DDR1-IN-5

English name

DDR1-IN-5

Chinese alias

DDR1-输入-5

English alias

CAS number

2416022-90-5

molecular formula

C22H13F3N6O

molecular weight

434.37 g/mol

Exact mass

≥99%

PSA

Logp

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