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Product introduction

DI-1859 is a potent, selective and covalent inhibitor of DCN1. DI-1859 inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 induces a robust increase of NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver damage. Form:Solid

Specs ⸢ View details ⸥

Chinese name

DI-1859

English name

DI-1859

Chinese alias

English alias

CAS number

2247061-09-0

molecular formula

C30H45N5O3S

molecular weight

555.78 g/mol

Exact mass

≥99%

PSA

Logp

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