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Product introduction

DC1Sme, a DC1 derivative, exhibits IC 50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin . DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer . Form:Solid IC50& Target:Duocarmycins

Specs ⸢ View details ⸥

Chinese name

DC1SMe

English name

DC1SMe

Chinese alias

直流1SMe

English alias

CAS number

501666-85-9

molecular formula

C35H30ClN5O4S2

molecular weight

684.23 g/mol

Exact mass

≥98%

PSA

181.000 Å²

Logp

5.800

Technical Documents

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