- Harmful effect： 每天给予少于2.5克去铁胺并监测治疗指数是避免此类并发症的最佳方法。急性副作用可能包括胃肠道投诉、过敏反应、皮肤变色、皮肤刺激和过敏反应。铁螯合和水溶性化合物ferioxamine的形成可能导致尿液呈玫瑰色。去铁胺可能增加特定病原体和侵袭性真菌（如毛霉菌、耶尔森菌和弧菌）感染的风险。ARDS是另一种潜在的罕见并发症，最常见于静脉输注该药物超过24小时时发生。
- Toxicity summary： 患者对去铁胺耐受性良好，该药物没有特定的解毒剂。预防措施和剂量减少在本文档的其他部分有描述。
- Regulatory information： REACH注册物质：状态：活跃 更新：2016-06-07 https://echa.europa.eu/registration-dossier/-/registered-dossier/17782
- interaction： 同时口服抗坏血酸(每天两次，每次0.5至1克)似乎能改善去铁胺在血色病中的螯合作用，特别是在存在维生素C缺乏的情况下。
- Hepatotoxicity： 可能性评分：E（不太可能引起明显的肝损伤）。
- Human toxicity extract： 给四名重型β地中海贫血患者静脉注射去铁胺，剂量高于先前报道的，以抵消输血引起的铁过载。其中两人出现视网膜异常，表现为夜盲和视野缺损，停药后有所改善。
- Hazard categories and classifications： 急性毒性 4 (97.1%)
- Non-human toxic extract： 给兔子玻璃体内注射5mg去铁胺被证明毒性很大，引起广泛的出血性坏死，特别影响视网膜的视杆和视锥细胞，并使视网膜电图消失。
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： 截至修订日期，未找到相关已发表信息。
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Deferoxamine 5mg
Deferoxamine 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥98%.
5mg
