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Product introduction
DAPT (GSI-IX)是一种新型γ-分泌酶抑制剂,抑制HEK 293细胞中全部Aβ产量, IC50为20 nM。A potent and specific inhibitor of γ-secretase. DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells. A potent and specific inhibitor of γ-secretase.
Chinese name
DAPT,γ-分泌酶抑制剂
English name
DAPT
Chinese alias
N-[N-(3,5-二氟苯乙酰)-L-丙氨酰]-S-苯甘氨酸叔丁酯 | (3,5-二氟苯乙酰基)-Ala-Phg-OtBu | (3,5-二氟苯乙酰基)-L-丙氨酰基-L-2-苯基甘氨酸叔丁酯
English alias
Glycine, N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)- | MRF-0000012 | (S)-tert-butyl 2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate | HY-13027G | KBio2_001007 | GSI IX | DWJXYEABWRJFSP-XOBRGWD
CAS number
208255-80-5
molecular formula
C23H26F2N2O4
molecular weight
432.46 g/mol
Exact mass
-
PSA
84.500 Ų
Logp
3.700
Technical Documents
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DAPT ≥98% 50/mg

DAPT ≥98% 50/mg Macklin 208255-80-5, available in complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials

item number:D832910-50mg
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