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Product introduction

Elacestrant (RAD1901) 是一种 estrogen receptor (ER) 降解剂 (SERD)，对 ERα 和 ERβ 的 IC50 值分别为 48 和 870 nM。Elacestrant 还能有效抑制 ER+ 乳腺癌细胞系在体内外的生长。 Elacestrant (RAD1901) is a selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo .

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Chinese name

elacestrant, 雌激素受体α降解剂

English name

elacestrant

Chinese alias

English alias

CAS number

722533-56-4

molecular formula

C30H38N2O2

molecular weight

458.6 g/mol

Exact mass

PSA

44.700 Å²

Logp

6.3

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