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Product introduction
EAI045是一种靶向特定耐药性的EGFR突变体的变构抑制剂。对野生型受体无作用。 EAI045是突变体 EGFR 的第四代变构抑制剂,在10 μM ATP时抑制EGFR,EGFRL858R,EGFRT790M 和 EGFRL858R/T790M 的IC50 值分别为1.9,0.019,0.19 和 0.002 μM。
Chinese name
EAI045, 表皮生长因子受体的异位调节剂
English name
EAI045
Chinese alias
-
English alias
2H-​Isoindole-​2-​acetamide,α-​(5-​fluoro-​2-​hydroxyphenyl)​-​1,​3-​dihydro-​1-​oxo-​N-​2-​thiazolyl- | (Z)-2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetimidic acid
CAS number
1942114-09-1
molecular formula
C19H14FN3O3S
molecular weight
383.4 g/mol
Exact mass
-
PSA
111.000 Ų
Logp
2.700
Technical Documents
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EAI045 10mM in DMSO 1ml

Macklin EAI045 10mM in DMSO 1ml, CAS 1942114-09-1, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:E688482-1ml
Product model:1ml
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Lead Time:30days
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