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Product introduction
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Chinese name
Fumitremorgin C, ABCG2 抑制剂
English name
Fumitremorgin C
Chinese alias
烟酸甲酯
English alias
(5as,12s,14as)-9-methoxy-12-(2-methylprop-1-en-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5h,14h-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione | F85534 | AKOS024457321 | SCHEMBL13113871 | SMR003082520 | HY-N2143 | fumitremorgin-c | (1S
CAS number
118974-02-0
molecular formula
C22H25N3O3
molecular weight
379.45 g/mol
Exact mass
≥95%
PSA
65.600 Ų
Logp
3.000
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Fumitremorgin C, ABCG2 inhibitor 1mg

Fumitremorgin C, ABCG2 inhibitor 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mg; ≥95%.

item number:F492230-1mg
Product model:1mg
level: 1mg; ≥95%
Lead Time:30days
sold 570 Items
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Specifications:

1mg

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