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Product introduction

GSK2606414是口服活性的PERK高活性抑制剂，IC50为0.4 nM。 GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed.

Specs ⸢ View details ⸥

Chinese name

GSK2606414

English name

GSK2606414

Chinese alias

English alias

AC-29016 | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone | Ethanone, 1-(5-(4-amino-7-methyl-7H-pyrrolo(2,3-d)pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl)-2-(3-(trifluoromethyl)phenyl)- | 1-[5-(4-a

CAS number

1337531-36-8

molecular formula

C24H20F3N5O

molecular weight

451.44 g/mol

Exact mass

10mM in DMSO

PSA

77.000 Å²

Logp

3.800

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