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Product introduction

GSK583 是一种高效、口服有效的、高选择性的 RIP2 Kinase 抑制剂，其 IC50 值为 5 nM。GSK583 可同时抑制TNF-α 和IL-6 的产生，IC50 值为 200 nM。 GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM.

Specs ⸢ View details ⸥

Chinese name

GSK583,RIPK2抑制剂, 受体相互作用丝氨酸/苏氨酸激酶 2 抑制剂

English name

GSK 583

Chinese alias

6-(叔丁基磺酰基)-N-(5-氟-1H-吲唑-3-基)喹啉-4-胺

English alias

GSK 583 | GSK-2616583A

CAS number

1346547-00-9

molecular formula

C20H19FN4O2S

molecular weight

398.45 g/mol

Exact mass

PSA

96.100 Å²

Logp

4.000

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