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Product introduction

GRL-0496 是一种有效的氯吡啶酯衍生的 SARS-CoV 3CLpro 抑制剂，IC50 值为 30 nM。GRL-0496 显示出最佳的 SARS-CoV 抗病毒活性，EC50 值为 6.9 μM GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM.

Specs ⸢ View details ⸥

Chinese name

GRL-0496

English name

GRL-0496

Chinese alias

ALP-POS-c59291d4-5 | compound 10 | GRL0496

English alias

1H-Indole-4-carboxylic acid 5-chloro-3-pyridinyl ester | 5-Chloro-3-pyridinyl 1H-indole-4-carboxylate | GRL 0496

CAS number

1087243-14-8

molecular formula

C14H9ClN2O2

molecular weight

272.69 g/mol

Exact mass

PSA

55.000 Å²

Logp

2.800

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