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Product introduction

GFB-12811 is a high selective and orally active CDK5 inhibitor with an IC 50 of 2.3 nM. GFB-12811 is highly selective over the other tested kinases (CDK1/2/6/7/9) Form:Solid IC50& Target:Cdk5/p25 2.3 nM (IC 50 ) CDK2/CycA 211 nM (IC 50 ) CDK7/Cyclin H/MAT1 718 nM (IC 50 ) CDK9/CycT1 894 nM (IC 50 )

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Chinese name

GFB-12811

English name

GFB-12811

Chinese alias

English alias

CAS number

2775311-17-4

molecular formula

C22H23F4N5O

molecular weight

449.44 g/mol

Exact mass

≥98%

PSA

Logp

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