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Product introduction

GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC 50 of 11.1 nM In Vitro GLPG2451 has an EC 50 value of 675 nM and an efficacy level of 147% of that of VX770 in G551D/F508del cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Cystic fibrosis transmembrane conductance regulator

Specs ⸢ View details ⸥

Chinese name

GLPG2451

English name

GLPG2451

Chinese alias

English alias

CAS number

2055015-61-5

molecular formula

C16H16F3N3O5S

molecular weight

419.38 g/mol

Exact mass

≥99%

PSA

140.000 Å²

Logp

2.100

Technical Documents

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