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Product introduction
GSK1070916是可逆的ATP竞争性Aurora B和C抑制剂,IC50分别为3.5 nM和6.5 nM。而对于Aurora A-TPX2复合物的IC50则为490 nM。 GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex.
Chinese name
GSK1070916, 丝氨酸/苏氨酸蛋白激酶 Aurora-C 抑制剂
English name
GSK1070916
Chinese alias
-
English alias
HY-70044 | AKOS005145558 | GTPL8358 | 3-(4-(4-(2-(3-((DIMETHYLAMINO)METHYL)PHENYL)-1H-PYRROLO(2,3-B)PYRIDIN-4-YL)-1-ETHYL-1H-PYRAZOL-3-YL)PHENYL)-1,1-DIMETHYLUREA | 8VLB51V7HO | NCGC00346648-10 | compound 17k [PMID 20420387] | MFCD22420815 | F17366 | s274
CAS number
942918-07-2
molecular formula
C30H33N7O
molecular weight
507.63 g/mol
Exact mass
-
PSA
82.100 Ų
Logp
3.9
Technical Documents
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GSK1070916 10mM in DMSO 1ml

GSK1070916 10mM in DMSO 1ml Macklin 942918-07-2, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:G792279-1ml
Product model:1ml
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Lead Time:30days
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