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Product introduction
Giredestrant (GDC-9545) 是一种新型 ER 拮抗剂,结合了理想的机制和临床前 DMPK 属性。Giredestrant 的高效体内功效可能是由于其具有高 ER 结合力、ER 信号传导的完全抑制和改善的 DMPK 特征。 Giredestrant (GDC-9545), a non-steroidal estrogen receptor (ER) ligand, is an orally active and selective ER antagonist. Giredestrant potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity
Chinese name
Giredestrant, 雌激素受体α降解剂
English name
Giredestrant
Chinese alias
吉雷德斯特兰
English alias
Giredestrant [USAN] | NSC827275 | NSC-827275 | AKOS040733254 | FLUCICLOVINE (18F) [WHO-DD] | AC-37111 | GDC9545 | GDC-9545 | MS-29682 | AFIMOXIFENE, Z-ISOMER | EX-A3541 | 5AzadC | AT22918 | 3-((1R,3R)-1-(2,6-Difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)am
CAS number
1953133-47-5
molecular formula
C27H31F5N4O
molecular weight
522.55 g/mol
Exact mass
≥98%
PSA
54.500 Ų
Logp
4.8
Technical Documents
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GDC-9545 ≥98% 5mg

GDC-9545 ≥98% 5mg Macklin 1953133-47-5, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:G995833-5mg
Product model:5mg
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Lead Time:30days
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