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亚油酸的脂氧合酶代谢产物。13（S）-HODE调节人多形核白细胞中的血小板活化因子，白三烯B4和甲酰-Met-Leu-Phe诱导的钙内流。13（S）-HODE发挥其抑制作用的机制仍不清楚。使用生物素化的15（S）-HETE作为探针来检测特异性结合15（S）-HETE的结合蛋白和/或受体，为13（S）-HODE-生物素的类似用途提供了基础。 The lipoxygenase metabolite of linoleic acid. 13(S)-HODE modulates the platelet-activating factor, leukotriene B4, and formyl-Met-Leu-Phe-induced calcium influx in human polymorphonuclear leukocytes. The mechanism that 13(S)-HODE uses to elicit its inhibitory effect is still unclear. The use of biotinylated 15(S)-HETE as a probe for detecting binding proteins and/or receptors that specifically bind 15(S)-HETE provides a basis for similar use of 13(S)-HODE-biotin.

Specs ⸢ View details ⸥

Chinese name

13（S）-HODE-生物素

English name

13(S)-HODE-biotin

Chinese alias

English alias

13(S)-hydroxy-N'-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)octadeca-9Z,11E-dienehydrazide

CAS number

1217458-58-6

molecular formula

C28H48N4O4S

molecular weight

536.8 g/mol

Exact mass

≥98%

PSA

Logp

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