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Product introduction

用途消除潜伏病毒的病毒潜伏期，以使病毒感染对抗病毒治疗敏感。在组蛋白赖氨酸脱甲基酶4A（KDM4A）抑制中，作为减少缺氧诱导因子信号传导的独特策略。恢复癌基因诱导的野生型小鼠胚胎成纤维细胞衰老。产品介绍 IOX1，是 2OG 氧合酶 (2OG oxygenases) 的有效广谱抑制剂，包括 JmjC 去甲基酶。IOX1 抑制 KDM4C，KDM4E，KDM2A，KDM3A 和 KDM6B 的 IC50 值分别为 0.6 μM，2.3 μM，1.8 μM，0.1 μM 和 1.4 μM。IOX1 抑制 ALKBH5。

Specs ⸢ View details ⸥

Chinese name

8-羟基喹啉-5-羧酸, egl-9 家族缺氧诱导因子 1 抑制剂

English name

8-Hydroxyquinoline-5-carboxylic Acid

Chinese alias

English alias

IOX1 | SCHEMBL6068195 | AKOS028109012 | Z1255461048 | 5-carboxy-8HQ | AMY6925 | PS-11320 | IOX1 compound | DTXSID20207236 | GTPL8230 | HY-12304 | 4bio | 8-Hydroxyquinoline-5-CarboxylicAcid | SB12855 | 5-Carboxy-8-hydroxyquinoline | IOX1, >=97% (HPLC) | SM

CAS number

5852-78-8

molecular formula

C10H7NO3

molecular weight

189.17 g/mol

Exact mass

PSA

70.400 Å²

Logp

1.800

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