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Product introduction

Thalidomide-4-OH (Cereblon ligand 2) 是一种基于 Thalidomide 的，可募集 CRBN 蛋白的 Cereblon 配体。Thalidomide-4-OH (Cereblon ligand 2) 可通过 linker 与靶蛋白配体连接，形成 PROTAC 分子。 Thalidomide-OH (Cereblon ligand 2, E3 ligase Ligand 2) is the Thalidomide-based Cereblon ligand that is applicable to the recruitment of CRBN protein. Thalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs.

Specs ⸢ View details ⸥

Chinese name

2-(2,6-二氧代 - 哌啶-3-基)-4-羟基 - 异吲哚-1,3-二酮

English name

2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

Chinese alias

English alias

CAS number

5054-59-1

molecular formula

C13H10N2O5

molecular weight

274.23 g/mol

Exact mass

≥95%

PSA

104.000 Å²

Logp

0.500

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