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Product introduction

Ibezapolstat (ACX-362E) 是一种首创的DNA 聚合酶 IIIC ( DNA pol IIIC) 的抑制剂，被开发用于艰难梭菌感染 (CDI) 的研究。Ibezapolstat 具有广谱的抗艰难梭菌活性，在体外对临床分离的 104 种菌株作用的 MIC 范围为1-8 μg/mL。 Ibezapolstat (ACX-362E) is a first-in-class DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat is developed for the research of C. difficile infection(CDI).

Specs ⸢ View details ⸥

Chinese name

Ibezapolstat

English name

Ibezapolstat

Chinese alias

伊贝扎波尔司他 | 伊贝泊司他

English alias

CAS number

1275582-97-2

molecular formula

C18H20Cl2N6O2

molecular weight

423.3 g/mol

Exact mass

PSA

83.800 Å²

Logp

1.600

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