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Product introduction

JZL 184 是一种有效的，选择性的且不可逆的 MAGL 抑制剂，可阻断脑膜中的 2-花生四烯酸甘油酯 (2-AG) 的水解 (IC50 为 8 nM)。JZL 184 对 MAGL 的选择性比 FAAH 高 300 倍以上。 application： JZL 184 has been used as an inhibitor of monoacylglycerol lipase to study its effect on human osteoblast differentiation and proliferation and postsynaptic neurons.

Specs ⸢ View details ⸥

Chinese name

JZL184, 单酰基甘油脂肪酶抑制剂

English name

JZL184

Chinese alias

English alias

4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl-(hydroxy)methyl)piperidine-1-carboxylate | AKOS024457824 | HY-15249 | Q27893460 | BRD-K45446451-001-01-9 | NCGC00263237-07 | HMS3652L12 | NSC763094 | NSC-763094 | US9133148, A | SCHEMBL15094611 | 4-[Bis(1,3-benz

CAS number

1101854-58-3

molecular formula

C27H24N2O9

molecular weight

520.5 g/mol

Exact mass

PSA

133.000 Å²

Logp

4.200

Technical Documents

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