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Product introduction

JND3229 是一种可逆性的 EGFR C797S 抑制剂，对 EGFR L858R/T790M/C797S 、EGFR WT 和 EGFR L858R/T790M 的 IC50 值分别为 5.8、6.8 和 30.5 nM。JND3229 具有较好的抗增殖活性，能有效地抑制体内肿瘤的生长。JND3229 可用于癌症，尤其是非小细胞癌的研究。 JND3229 JND3229 is a potent reversible inhibitor of EGFR C797S with an IC50 value of 5.8 nM. JND3229 also potently suppresses EGFR L858R/T790M and EGFR WT with IC50 values of 30.5 nM and 6.8 nM, respectively.

Specs ⸢ View details ⸥

Chinese name

JND3229

English name

JND3229

Chinese alias

English alias

N-(trans-4-(3-(2-Chlorophenyl)-7-((3-methyl-4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)cyclohexyl)propionamide

CAS number

2260886-64-2

molecular formula

C33H41ClN8O2

molecular weight

617.18 g/mol

Exact mass

PSA

96.900 Å²

Logp

5.000

Technical Documents

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JND3229 98% 5mg

Name: JND3229 98% 5mg
Brand: 麦克林
SKU: J910754-5mg

JND3229 98% 5mg CAS 2260886-64-2, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：J910754-5mg

Product model：5mg

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Lead Time：30days

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JND3229 98% 5mg

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