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Product introduction

Ki8751是高活性VEGFR2选择性抑制剂，IC50为0.9 nM，比对c-Kit，PDGFRα和FGFR-2的抑制性高40倍，对EGFR，HGFR和 InsR几乎无活性。A cell-permeable Flk-1 (VEGFR-2) and c-Kit inhibitor Ki8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM, >40-fold selective for VEGFR2 than c-Kit, PDGFRα and FGFR-2, little activity to EGFR, HGFR and InsR. A cell-permeable Flk-1 (VEGFR-2) and c-Kit inhibitor

Specs ⸢ View details ⸥

Chinese name

Ki8751,VEGFR-2酪氨酸激酶抑制剂

English name

Ki8751

Chinese alias

English alias

CAS number

228559-41-9

molecular formula

C24H18F3N3O4

molecular weight

469.41 g/mol

Exact mass

≥98%

PSA

81.700 Å²

Logp

4.500

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