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Product introduction
KW-2449能较强地抑制Flt3,IC50为6.6 nM,对FGFR1,Bcr-Abl和Aurora A的抑制性适中,而对 PDGFRβ,IGF-1R,EGFR则无抑制性。A multikinase inhibitor of FLT3, ABL, ABL-T315I, and Aurora kinase。 KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. A multikinase inhibitor of FLT3, ABL, ABL-T315I, and Aurora kinase。
Chinese name
KW-2449,抑制FLT3,ABL和Aurora激酶, 酪氨酸蛋白激酶 ABL 抑制剂
English name
KW-2449
Chinese alias
-
English alias
(E)-1-{4-[2-(1H-indazol-3-yl)vinyl]benzoyl}piperazine | NCGC00346569-07 | (E)-(4-(2-(1H-Indazol-3-yl)vinyl)-phenyl)(piperazin-1-yl)methanone | (E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone | AC-28419 | NSC800778 | NSC-800778 | KW-2449
CAS number
1000669-72-6
molecular formula
C20H20N4O
molecular weight
332.4 g/mol
Exact mass
-
PSA
61.000 Ų
Logp
2.700
Technical Documents
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KW-2449 98% 100mg

KW-2449 98% 100mg CAS 1000669-72-6, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:K855211-100mg
Product model:100mg
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Lead Time:30days
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