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Product introduction

LFM-A13是一种特异性布鲁顿氏酪氨酸激酶(BTK)抑制剂，IC50为2.5 μM,选择性比其他蛋白激酶，包括JAK1，JAK2，HCK，EGFR，和 IRK高100多倍。 LFM-A13 是一种有效的 BTK，JAK2，PLK 抑制剂，可抑制 BTK，Plx1 和 PLK3 的活性，IC50 分别为 2.5 μM，10 μM 和 61 μM。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specs ⸢ View details ⸥

Chinese name

LFM-A13, 布鲁顿酪氨酸激酶抑制剂

English name

LFM-A13

Chinese alias

2-氰基-N-(2,5-二溴苯基)-3-羟基丁-2-烯酰胺

English alias

CCG-100654 | NCGC00025100-02 | Lopac0_000650 | a-Cyano-b-hydroxy-b-methyl-N-(2,5-dibromophenyl)propenamide | BDBM50552060 | DTXSID101017390 | K00067 | L 8789 | alpha-Cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide | SR-01000075965-3 | (Z)-

CAS number

244240-24-2

molecular formula

C11H8Br2N2O2

molecular weight

360 g/mol

Exact mass

PSA

73.100 Å²

Logp

3.800

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