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Product introduction
LDN-193189 (DM3189) 2HCl是一种选择性 BMP 信号抑制剂,抑制 ALK1, ALK2, ALK3和 ALK6,在激酶测定中的 IC50 分别为 0.8 nM、0.8 nM、5.3 nM 和 16.7 nM。LDN-193189 抑制BMP I型受体ALK2和ALK3的转录活性,在C2C12细胞中IC50分别为5 nM和30 nM,作用于BMP比作用于TGF-β选择性高200倍。
Chinese name
LDN 193189 dihydrochloride
English name
LDN 193189 dihydrochloride
Chinese alias
4-[6-[4-(1-哌嗪基)苯基]吡唑并[1,5-a]嘧啶-3-基]喹啉二盐酸盐 | LDN 193189 二盐酸盐
English alias
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride | DM-3189 2HCl
CAS number
1435934-00-1
molecular formula
C25H24Cl2N6
molecular weight
479.4 g/mol
Exact mass
10mM in Water
PSA
58.400 Ų
Logp
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LDN-193189 2HCl 10mM in Water 1ml

LDN-193189 2HCl 10mM in Water 1ml Macklin 1435934-00-1, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:L792425-1ml
Product model:1ml
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Lead Time:30days
sold 332 Items
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