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Product introduction
Ceritinib dihydrochloride (LDK378 dihydrochloride) 是一种选择性,口服可生物利用且具有 ATP 竞争性的 ALK 酪氨酸激酶抑制剂,IC50 为 200 pM。Ceritinib dihydrochloride (LDK378 dihydrochloride) 还抑制 IGF-1R,InsR 和 STK22D,IC50 值分别为 8、7 和 23 nM。Ceritinib dihydrochloride (LDK378 dihydrochloride) 显示出良好的抗肿瘤效力。
Chinese name
双盐酸盐色瑞替尼
English name
Ceritinib dihydrochloride
Chinese alias
色瑞替尼二盐酸盐
English alias
5-Chloro-n2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine 2HCl | Ceritinib dihydrochloride | LDK378 2HCl (Ceritinib) | UNII-08381UU98P | 2,4-Pyrimidinediamine, 5-chloro-N4-[2-[(1-methylethyl)sulfon
CAS number
1380575-43-8
molecular formula
C28H38Cl3N5O3S
molecular weight
631.06 g/mol
Exact mass
≥98%
PSA
114.000 Ų
Logp
7.243
Technical Documents
「No technical documents」
Related
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Research chemical CAS 1380575-43-8 10mM 1ml

Research chemical CAS 1380575-43-8 10mM 1ml, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:L794043-1ml
Product model:1ml
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Lead Time:30days
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