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Product introduction

Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC 50 s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Form:Solid IC50& Target:Protease Cleavable Cleavable

Specs ⸢ View details ⸥

Chinese name

Mc-Val-Cit-PAB-Cl

English name

Mc-Val-Cit-PAB-Cl

Chinese alias

缬氨酸-西他滨-PAB-Cl

English alias

N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(chloromethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-6-(2,5-dioxopyrrol-1-yl)hexanamide | N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(chloromethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl

CAS number

1639351-92-0

molecular formula

C28H39ClN6O6

molecular weight

591.10 g/mol

Exact mass

PSA

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