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Product introduction

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) 是 ADC 毒素 Exatecan 和连接子 Mal-Val-Ala-PAB-N(SO2Me) 的偶联物。Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 可用于合成 ADC FZ-AD005。FZ-AD005 是一种靶向 delta 样配体 3 (DLL3, KD=58.3 pM) 的 ADC，对 SCLC 癌症具有抗肿瘤活性。体外研究： ADC 由一种抗体组成，ADC 细胞毒素通过 ADC 接头连接到该抗体上。 Mal Val Ala PAB-N (SO2Me) - Exatecan (Compound LE14) is a conjugate of ADC toxin Exatecan and linker Mal Val Ala PAB-N (SO2Me). Mal Val-Ala-PAB-N (SO2Me) - Hexatecan can be used to synthesize ADC FZ-AD005. FZ-AD005 is an ADC targeting delta like ligand 3 (DLL3, KD=58.3 pM) with anti-tumor activity against SCLC cancer. In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) In vitro studies: ADC is composed of an antibody, and ADC cytotoxin is connected to the antibody through an ADC adapter.

Specs ⸢ View details ⸥

Chinese name

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan

English name

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan

Chinese alias

English alias

CAS number

2575682-08-3

molecular formula

C56H65FN8O15S

molecular weight

1141.22 g/mol

Exact mass

≥96%

PSA

Logp

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Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 1mg

Name: Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 1mg
Brand: 阿拉丁
SKU: M767873-1mg

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mg; ≥96%.

item number：M767873-1mg

Product model：1mg

level： 1mg; ≥96%

Lead Time：30days

sold 488 Items

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1mg

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Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 1mg

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