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Product introduction
储存在-20℃。存放在干燥的条件下。该产品最多可存储12个月。 MNS (NSC 170724) 是 β-硝基苯乙烯衍生物,是一种有效的酪氨酸激酶抑制剂和广谱抗血小板药物。MNS 完全抑制 U46619、ADP、花生四烯酸、胶原和凝血酶诱导的血小板聚集,IC50 值分别为 2.1、4.1、5.8、7.0 和 12.7 μM。MNS 抑制 Src、Syk 和 FAK,IC50 分别为 27.3、2.8 和 97.6 μM。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. product description: A cell-permeable nitrostyrene compound that acts as a selective inhibitor of Syk kinase activity (IC50 = 2.5 µM). It inhibits Src only at much higher concentrations (IC50 = 29.3 µM) and exhibits little effect against Fak and JAK2. Shown to potently inhibit platelet aggregation induced by various stimulators, including U46619, ADP, arachidonic acid, collagen, thrombin, ionophore A23187, and PDBu (IC50 ranges from 2.1 to 25.9 µM). Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic ac
Chinese name
MDBN,不可逆p97抑制剂, 脾相关酪氨酸激酶抑制剂
English name
MDBN
Chinese alias
-
English alias
5-[(E)-2-nitroethenyl]-2H-1,3-benzodioxole | AI3-02050 | NCGC00261282-01 | NSC 105303 | Syk Inhibitor III | 5-(2-Nitro-vinyl)-benzo[1,3]dioxole | EN300-83338 | SBB007833 | BDBM50155928 | Ethene, 1-(3,4-methylendioxyphenyl)-2-nitro- | NCGC00186015-06 | 3,4
CAS number
1485-00-3
molecular formula
C9H7NO4
molecular weight
193.16 g/mol
Exact mass
-
PSA
64.300 Ų
Logp
2.400
Technical Documents
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MNS (3, 4-Methylenedioxy-β-nitrostyrene, MDBN) 10mM in DMSO 1ml

MNS (3, 4-Methylenedioxy-β-nitrostyrene, MDBN) 10mM in DMSO 1ml Macklin 1485-00-3, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:M793644-1ml
Product model:1ml
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Lead Time:30days
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