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Product introduction
Motesanib (AMG-706)是ATP竞争性VEGFR1,2,3抑制剂,IC50分别为 2 nM,3 nM和6 nM,对c-Kit的IC50为8 nM。An inhibitor of Flk-1, Flt-4, PDGFR-β and c-Kit. Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. An inhibitor of Flk-1, Flt-4, PDGFR-β and c-Kit.
Chinese name
莫特塞尼, 血小板衍生生长因子受体抑制剂
English name
Motesanib
Chinese alias
莫特塞尼
English alias
N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide | NSC800801 | NSC-800801 | HMS3244B09 | HY-10228 | N-(3,3-Dimethyl-2,3-dihydro-1H-indol-6-yl)-2-((pyridin-4-ylmethyl)amino)pyridine-3-carboxamide | SCHEMBL2416976 | D
CAS number
453562-69-1
molecular formula
C22H23N5O
molecular weight
373.46 g/mol
Exact mass
-
PSA
78.900 Ų
Logp
3.9
Technical Documents
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Motesanib 10mM in DMSO 1ml

Motesanib 10mM in DMSO 1ml Macklin 453562-69-1, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:M794824-1ml
Product model:1ml
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Lead Time:30days
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