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Product introduction
Mivebresib (ABBV-075) 是一种新型的 BET family bromodomain 抑制剂。以相似的亲和力结合BRD2/4/T的溴区(Ki值在1-2.2 nM间),具有高度选择性。对BRD3的效力比较低(Ki=12.2 nM),对CREBBP具有中等活性(Ki=87 μM)。Mivebresib(ABBV-075) 可有效地触发多种肿瘤细胞的凋亡。
Chinese name
米维布塞, 含溴结构域 4 的抑制剂
English name
Mivebresib
Chinese alias
-
English alias
Mivebresib [USAN] | Mivebresib; ABBV-075 | Mivebresib | SCHEMBL15068241 | AKOS030628486 | N-[4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide | N-[4-(2,4-difluorophenoxy)-3-{6-methyl-7-oxo-1H,6H,7H-pyrrolo[2
CAS number
1445993-26-9
molecular formula
C22H19F2N3O4S
molecular weight
459.47 g/mol
Exact mass
-
PSA
99.900 Ų
Logp
2.900
Technical Documents
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Mivebresib(ABBV-075) 99% 5mg

Mivebresib(ABBV-075) 99% 5mg CAS 1445993-26-9, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:M872720-5mg
Product model:5mg
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Lead Time:30days
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