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Product introduction

NSC319726是突变型p53R175再活化剂，能抑制表达p53R175的成纤维细胞增殖，IC50值为8nM，对野生型p53细胞无抑制作用。 NSC319726 is a p53(R175) mutant reactivator, exhibits growth inhibition in cells expressing mutant p53, with IC50 of 8 nM for p53(R175) mutant, shows no inhibition for p53 wild-type cells.

Specs ⸢ View details ⸥

Chinese name

NSC 319726,p53（R175）突变激活剂

English name

NSC 319726

Chinese alias

English alias

NSC 319726 | s7149 | BRD-K99170882-001-01-9 | A899911 | Azetidinecarbothioic acid, [1-(2-pyridinyl)ethylidene] hydrazide | CCG-35689 | AKOS024458479 | N'-(1-(Pyridin-2-yl)ethylidene)azetidine-1-carbothiohydrazide | EX-A2113 | LS-13960 | N-[(E)-1-pyridin-2

CAS number

71555-25-4

molecular formula

C11H14N4S

molecular weight

234.32 g/mol

Exact mass

≥95%

PSA

72.600 Å²

Logp

1.400

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